【摘要】用ＰＣＲ－ＲＦＬＰ方法对江浙沪籍汉族５５例病理性近视眼（ＰＭ）患者的ＨＬＡⅡ类ＤＱＢ１基因的第二个外显子进行了基因分型。结果发现ＨＬＡ－ＤＱＢ１＊０２０１、＊０３０３、＊０４０１等位基因在ＰＭ患者中和正常人中的分布有显著的差异（Ｐｃ＜０．０５，ＡＦ分别为０．１６３６，０．１０９１，０．１６３６，０．１０９１ｖｓ．０．０４００，０．０３００，０．０４００，０．０２００），可能与ＰＭ的致病相关。ＤＱＢ
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